Hepato-neuro lab

Mélanie Tremblay, M.Sc.

Mélanie Tremblay

 Research Assistant

Direction:

  • Dr Christopher Rose

 2007 - now

  Social media profiles :


Related Publications

Neurological dysfunction is improved after faecal microbiota transplantation in rats with bile duct ligated-induced chronic liver disease.

Neurological dysfunction is improved after faecal microbiota transplantation in rats with bile duct ligated-induced chronic liver disease.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, André Marette, Chantal Bémeur, Christopher F. Rose.

Constant alcohol consumption exacerbates hepatic encephalopathy and induces neuronal cell loss in rats with chronic liver disease.

Constant alcohol consumption exacerbates hepatic encephalopathy and induces neuronal cell loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Xiaoru Chen, Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

La transplantation de microbiote fécal améliore les troubles neurologiques chez les rats avec une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Kraine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

L’acide urique comme facteur de risque pour les complications cognitives de la cirrhose du foie : développement et validation d’un nouveau modèle murin.

Sydnée L’Écuyer, Alexandra Matesan, Farzaneh Tamnanloo, Mariana Oliveira, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Exacerbation du déclin neurologique et perte cellulaire neuronale causée par la consommation continuelle d’alcool chez les rats ayant une maladie de foie chronique.

Farzaneh Tamnanloo, Xiaoru Chen, Mélanie Tremblay, Christopher F. Rose.

Oral

Étude transversale : Dépistage à long terme de la malnutrition, de la sarcopénie et de la fragilité physique chez les receveurs d’une transplantation hépatique.

Amal Trigui, Mélanie Tremblay, C. F. Rose, Chantal Bémeur.

Oral

L’acide urique comme facteur de risque pour les complications cognitives de la cirrhose du foie : développement et validation d’un nouveau modèle murin.

Sydnée L’Écuyer, Alexandra Matesan, Farzaneh Tamnanloo, Mariana Oliveira, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Oral

Le rôle de la consommation constante d'alcool sur le déclin neurologique et la perte de cellules neuronales chez les rats atteints d'une maladie hépatique chronique.

Farzaneh Tamnanloo, Xiaoru Chen, Mélanie Tremblay, Christopher F. Rose.

Oral

La transplantation de microbiote fécal améliore les troubles neurologiques chez les rats avec une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Kraine Dubois, Mélanie Tremblay, Chantal Bémeur, F. Rose Christopher.

Oral

Hyperuricemia as an implicated factor in cognitive impairments in chronic liver disease: developing a new murine model.

Sydnée L’Écuyer, Alexandra Matesan, Farzaneh Tamnanloo, Mariana Oliveira, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Constant alcohol consumption exacerbates neurological decline and causes neuronal cell loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Xiaoru Chen, Mélanie Tremblay, Christopher F. Rose.

Neurological impairment in rats with bile duct ligated-induced chronic liver disease are improved after faecal microbiota transplantation.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

La transplantation de microbiote fécal améliore l’atteinte neurologique chez les rats ayant subi une la ligature du canal biliaire induisant une maladie hépatique chronique.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, F. Rose Christopher.

Oral

Le guide la nutrition pour la cirrhose : est-ce une ressource éducative adaptée aux patients atteints de maladie hépatique chronique?

Manila Sophasath, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral

Dépistage à long terme de la malnutrition, de la sarcopénie et de la fragilité physique chez les receveurs d’une transplantation hépatique : étude transversale.

Amal Trigui, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Prevalence of overweight and obesity in patients on the liver transplant waiting list: Experience of a referral center, Centre hospitalier de l’Université de Montréal (CHUM).

Isaac Ruiz, Mélanie Tremblay, Crystèle Hogue, Amal Trigui, Geneviève Huard, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Constant alcohol consumption exacerbates neurological decline and causesneuronal cell loss in rats with chronic liver disease

Farzaneh Tamnanloo, Xiaoru Chen, Mélanie Tremblay, Christopher F. Rose.

Le guide La nutrition pour la cirrhose : une ressource éducative adéquate pour nos patients ?

Le guide La nutrition pour la cirrhose : une ressource éducative adéquate pour nos patients ?

Manila Sophasath, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Étude longitudinale: Suivi de l’état nutritionnel, de la qualité de vie et de la fonction musculaire des patients sur la liste d

Étude longitudinale: Suivi de l’état nutritionnel, de la qualité de vie et de la fonction musculaire des patients sur la liste d'attente pour une greffe de foie.

Amal Trigui, Joann Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral
La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d

La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d'une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Long-term screening for malnutrition, sarcopenia, and physical frailty in liver transplant recipients: a cross-sectional study.

Long-term screening for malnutrition, sarcopenia, and physical frailty in liver transplant recipients: a cross-sectional study.

Amal Trigui, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Nutritional education strategies for patients with cirrhosis: Evaluation of the Nutrition in cirrhosis guide.

Nutritional education strategies for patients with cirrhosis: Evaluation of the Nutrition in cirrhosis guide.

Manila Sophasath, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Neurological dysfunction is improved after faecal microbiota transplantation in rats with bile duct ligated-induced chronic liver disease.

Neurological dysfunction is improved after faecal microbiota transplantation in rats with bile duct ligated-induced chronic liver disease.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, André Marette, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Nutritional education strategies for cirrhotic patients : Evaluation of a nutrition guide.

Nutritional education strategies for cirrhotic patients : Evaluation of a nutrition guide.

Manila Sophasath, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Longitudinal analysis of nutritional risk, muscle function and quality of life of patients with end stage liver disease waiting for liver transplantation.

Longitudinal analysis of nutritional risk, muscle function and quality of life of patients with end stage liver disease waiting for liver transplantation.

Amal Trigui, Joann Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral
Constant alcohol consumption exacerbates hepatic encephalopathy inducing neuronal cell loss in rats with chronic liver disease.

Constant alcohol consumption exacerbates hepatic encephalopathy inducing neuronal cell loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Mélanie Tremblay, Christopher F. Rose.

Hyperuricemia as a risk factor for cognitive impairments in chronic liver disease: developing a new murine model.

Hyperuricemia as a risk factor for cognitive impairments in chronic liver disease: developing a new murine model.

Sydnée L'Écuyer, Alexandra Matesan, Farzaneh Tamnanloo, Mariana Oliveira, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Neurological impairment in rats with bile duct ligated-induced chronic liver disease are improved after faecal microbiota transplantation.

Neurological impairment in rats with bile duct ligated-induced chronic liver disease are improved after faecal microbiota transplantation.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Évolution du risque nutritionnel, de la qualité de vie et de la fonction musculaire des patients en attente d’une transplantation hépatique : Étude longitudinale.

Amal Trigui, Joann Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

La transplantation de microbiote fécal améliore l’atteinte neurologique chez les rats avec une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Les effets de l’alcool éthylique sur le cervelet des rats cirrhotiques.

Les effets de l’alcool éthylique sur le cervelet des rats cirrhotiques.

Samia Cherkaoui, Farzaneh Tamnanloo, Xiaoru Chen, Mélanie Tremblay, Christopher F. Rose.

Oral

Longitudinal evolution of nutritional risk and muscle function of patients waiting for liver transplantation and the effect of early nutritional intervention following the transplantation

Amal Trigui, Joan Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Repeated ammonia-induced episodes of hepatic encephalopathy leads to neuronal cell loss in rats with chronic liver disease.

Repeated ammonia-induced episodes of hepatic encephalopathy leads to neuronal cell loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Faecal microbiota transplantation improves neurological impairment in rats with chronic liver disease.

Faecal microbiota transplantation improves neurological impairment in rats with chronic liver disease.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d'une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher Rose.

Des épisodes d’encéphalopathie hépatique induits par l’ammoniaque mènent à des dommages cellulaires neuronaux chez les rats avec ligation de voie biliaire.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Oral

Évolution de l’état nutritionnel, de la qualité de vie et de la fonction musculaire des patients en attente d’une transplantation hépatique.

Amal Trigui, Joan Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral

Évolution de l’état nutritionnel, de la qualité de vie et de la fonction musculaire des patients en attente d’une transplantation hépatique et l'effet d'une intervention nutritionnelle précoce après la transplantation sur ces paramètres.

Amal Trigui, Joan Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

OpenAccess
Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile-duct ligated rats.

Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile-duct ligated rats.

Mariana Macedo de Oliveira, Alexis Monnet-Aimard, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Evolution of nutritional risk, muscle function and quality of life of cirrhotic patients waiting for liver transplantation.

Evolution of nutritional risk, muscle function and quality of life of cirrhotic patients waiting for liver transplantation.

Amal Trigui, Joan Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Impact de la diète riche en protéines sur le stress oxydatif systémique chez les rats cirrhotiques par ligation du canal biliaire.

Karim El-Hajj-Moussa-Ali, Katerina Kroupina, Mélanie Tremblay, C. F. Rose.

Multiple hyperammonemia-induced episodes of HE leads to neuronal loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Implication de l’acide urique dans la pathophysiologie de l’encéphalopathie hépatique.

Sydnée L'Écuyer, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Oral

La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d'une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher Rose.

Multiple hyperammonemia-induced episodes of HE leads to neuronal loss in rats with chronic liver disease.

Multiple hyperammonemia-induced episodes of HE leads to neuronal loss in rats with chronic liver disease.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Faecal microbiota transplantation improves neurological impairment in rats with bile-duct ligated induced chronic liver disease.

Faecal microbiota transplantation improves neurological impairment in rats with bile-duct ligated induced chronic liver disease.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Targeting glutamine synthetase in endothelial cells of the blood-brain barrier to treat hyperammonemia and hepatic encephalopathy.

Targeting glutamine synthetase in endothelial cells of the blood-brain barrier to treat hyperammonemia and hepatic encephalopathy.

Mariana M. Oliveira, Ole-Martin Fuskevåg, Mélanie Tremblay, Christopher Rose.

Impact of sex on muscle mass loss and hepatic encephalopathy in rats with chronic liver disease.

Impact of sex on muscle mass loss and hepatic encephalopathy in rats with chronic liver disease.

Mariana M. Oliveira, Alexis Monnet-Aimard, Cristina Bosoi, Mélanie Tremblay, Christopher Rose.

Oral
La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d

La transplantation de microbiote fécal améliore la déficience neurologique chez les rats atteints d'une maladie hépatique chronique induite par la ligature du canal biliaire.

Alexandre Bourgeois, Felix Veillette, Mariana Oliveira, Karine Dubois, Mélanie Tremblay, Chantal Bémeur, Christopher Rose.

Évaluation de ressources éducatives en nutrition destinées aux patients atteints de cirrhose : Un projet en quatre volets.

Manila Sophasath, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Évolution de l’état nutritionnel, de la qualité de vie et de la fonction musculaire des patients en attente d’une transplantation hépatique.

Amal Trigui, Yvette Mukaneza, Mélanie Tremblay, Joann Maxwell, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Ammonia-induced episodic HE leads to neuronal cell injury in bile-duct ligated rats

Ammonia-induced episodic HE leads to neuronal cell injury in bile-duct ligated rats

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Implication de l’acide urique dans la pathophysiologie de l’encéphalopathie hépatique.

Implication de l’acide urique dans la pathophysiologie de l’encéphalopathie hépatique.

Sydnée L'Écuyer, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Oral
The effect of early nutritional intervention on muscle mass following liver transplantation.

The effect of early nutritional intervention on muscle mass following liver transplantation.

Amal Trigui, Joann Maxwell, Geneviève Huard, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

OpenAccess
Renal dysfunction independently predicts muscle mass loss in patients following liver transplantation.

Renal dysfunction independently predicts muscle mass loss in patients following liver transplantation.

Mimosa Nguyen, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Optimisation de la masse musculaire grâce à une intervention nutritionnelle précoce chez les patients ayant reçu une transplantation hépatique.

Amal Trigui, Yvette Mukaneza, Mélanie Tremblay, Joan Maxwell, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Impact of sex on development of hepatic encephalopathy, sarcopenia and pathogenic factors in rats with chronic liver disease

Impact of sex on development of hepatic encephalopathy, sarcopenia and pathogenic factors in rats with chronic liver disease

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Episodic hepatic encephalopathy induces neuronal cell injury in rats with chronic liver disease

Episodic hepatic encephalopathy induces neuronal cell injury in rats with chronic liver disease

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Oral
Sex disparity on the development of HE: impact of ammonia and ROS in the development of brain edema and hepatic encephalopathy severity in BDL rats

Sex disparity on the development of HE: impact of ammonia and ROS in the development of brain edema and hepatic encephalopathy severity in BDL rats

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Effectuer la diète FODMAP via une plateforme web : impact sur la qualité de vie et les symptômes des gens atteints du syndrome de l’intestin irritable

Sandrine Laforce, Mélanie Tremblay, Yvette Mukaneza, Benoît Lamarche, Cécile Delawarde-Saïs, Mickael Bouin, Chantal Bémeur.

L’effet d’une intervention nutritionelle précoce sur la masse musculaire suite à la transplantation hépatique.

Amal Trigui, Yvette Mukaneza, Mélanie Tremblay, Joann Maxwell, Geneviève Huard, F. Rose Christopher, C. Bémeur.

Evaluation of the Nutrition in Cirrhosis Guide : an implementation study.

Evaluation of the Nutrition in Cirrhosis Guide : an implementation study.

Manila Sophasath, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, C. Bémeur.

Obese-induced brain sphingolipid dysregulation in bile-duct ligated rats accelerates and exacerbates hepatic encephalopathy.

Obese-induced brain sphingolipid dysregulation in bile-duct ligated rats accelerates and exacerbates hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Role of sex on the development of sarcopenia and ammonia metabolism in bile-duct ligated rats.

Role of sex on the development of sarcopenia and ammonia metabolism in bile-duct ligated rats.

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Régime hyperprotéiné dans l'encéphalopathie hépatique : précipitant ou protecteur ?

Katerina Kroupina, Karine Dubois, Mélanie Tremblay, Christopher Rose.

Implication de l’acide urique dans le développement des déficits cognitifs associés à l’encéphalopathie hépatique.

Sydnée L'Écuyer, Karine Dubois, Mélanie Tremblay, Emmanuel Charbonney, Christopher Rose.

Sex impacts muscle loss and ammonia metabolism in rats with chronic liver disease.

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Implication de l’acide urique dans le développement des déficits cognitifs associés à l’encéphalopathie hépatique.

Sydnée L'Écuyer, Karine Dubois, Mélanie Tremblay, Emmanuel Charbonney, Christopher Rose.

Ammonia-induced episodic HE leads to neuronal cell injury in bile-duct ligated rats.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

La diète FODMAP via une plateforme web : impact sur la qualité de vie et les symptômes des gens atteints du syndrome de l’intestin irritable

Sandrine Laforce, Yvette Mukaneza, Mélanie Tremblay, Benoît Lamarche, Cécile Delawarde-Saïas, Mickael Bouin, Chantal Bémeur.

Le guide de nutrition pour la cirrhose : quel est son effet chez les gens atteints de maladie hépatique chronique et leurs proches aidants?

Manila Sophasath, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

L’effet d’une intervention nutritionnelle précoce sur la masse musculaire chez les patients ayant reçu une transplantation hépatique.

Amal Trigui, Yvette Mukaneza, Mélanie Tremblay, Joann Maxwell, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

La barrière hémato-encéphalique lors d

La barrière hémato-encéphalique lors d'encéphalopathie hépatique épisodique.

Mihai Alexandru Popovici, Farzaneh Tamnanloo, Mélanie Tremblay, Christopher F. Rose.

Régime hyperprotéiné dans l

Régime hyperprotéiné dans l'encéphalopathie hépatique : précipitant ou protecteur ?

Katerina Kroupina, Karine Dubois, Mélanie Tremblay, Christopher F. Rose.

La diète FODMAP via une plateforme web : impact sur la qualité de vie et les symptômes des gens atteints du syndrome de l

La diète FODMAP via une plateforme web : impact sur la qualité de vie et les symptômes des gens atteints du syndrome de l'intestin irritable

Sandrine Laforce, Yvette Mukaneza, Mélanie Tremblay, Benoît Lamarche, Cécile Delawarde-Saïas, Mickael Bouin, Chantal Bémeur.

Implication de l’acide urique dans le développement des déficits cognitifs associés à l’encéphalopathie hépatique.

Implication de l’acide urique dans le développement des déficits cognitifs associés à l’encéphalopathie hépatique.

Sydnée L'Écuyer, Karine Dubois, Mélanie Tremblay, Emmanuel Charbonney, Christopher F. Rose.

Online-based psychometric assessment battery as a predictive test for Hepatic Encephalopathy in cirrhotic patients.

Online-based psychometric assessment battery as a predictive test for Hepatic Encephalopathy in cirrhotic patients.

Silícia Ane Tres, Mélanie Tremblay, Yvette Mukaneza, Christopher F. Rose.

L’effet d’une intervention nutritionnelle précoce sur la masse musculaire chez les patients ayant reçu une transplantation hépatique.

L’effet d’une intervention nutritionnelle précoce sur la masse musculaire chez les patients ayant reçu une transplantation hépatique.

Amal Trigui, Yvette Mukaneza, Mélanie Tremblay, Joann Maxwell, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Effects of sex on liver disease: impact on sarcopenia and ammonia metabolism in bile-duct ligated rats.

Effects of sex on liver disease: impact on sarcopenia and ammonia metabolism in bile-duct ligated rats.

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Ammonia-induced episodic HE leads to neuronal cell injury in bile-duct ligated rats.

Ammonia-induced episodic HE leads to neuronal cell injury in bile-duct ligated rats.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Repeated hyperammonemic insults leads to irreversible brain injury in bile-duct ligated rats.

Repeated hyperammonemic insults leads to irreversible brain injury in bile-duct ligated rats.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Dysregulation of sphingolipids in obese-cirrhotic rats aggravates hepatic encephalopathy.

Dysregulation of sphingolipids in obese-cirrhotic rats aggravates hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Sex disparity in the development of brain edema and hepatic encephalopathy severity in BDL rats.

Sex disparity in the development of brain edema and hepatic encephalopathy severity in BDL rats.

Mariana Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

The Nutrition in Cirrhosis Guide: a useful education tool for in people suffering from chronic liver disease and their caregivers?

The Nutrition in Cirrhosis Guide: a useful education tool for in people suffering from chronic liver disease and their caregivers?

Manila Sophasath, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

The Nutrition in Cirrhosis Guide: Potential beneficial effects in cirrhotic patients and caregivers.

The Nutrition in Cirrhosis Guide: Potential beneficial effects in cirrhotic patients and caregivers.

Manila Sophasath, Yvette Mukaneza, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Le Guide de nutrition pour la cirrhose : effets potentiellement bénéfiques chez les patients atteints de maladie hépatique chronique et leurs proches aidants.

Manila Sophasath, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral
Les métaux lourds et l’encéphalopathie hépatique.

Les métaux lourds et l’encéphalopathie hépatique.

Mihai Alexandru Popovici, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Elevated Serum Liver-Type Fatty Acid Binding Protein Levels in Non-acetaminophen Acute Liver Failure Patients with Organ Dysfunction.

Elevated Serum Liver-Type Fatty Acid Binding Protein Levels in Non-acetaminophen Acute Liver Failure Patients with Organ Dysfunction.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, U. S. Acute Liver Failure Study Group.

OpenAccess
Bile-duct ligation renders the brain susceptible to hypotension induced neuronal degeneration: implications of ammonia.

Bile-duct ligation renders the brain susceptible to hypotension induced neuronal degeneration: implications of ammonia.

Marc-André Clément, Cristina R. Bosoi, Mariana M. Oliveira, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Stroop EncephalApp as a predictive test for overt Hepatic Encephalopathy in cirrhotic patients.

Silicia A. Très, Mélanie Tremblay, Yvette Mukaneza, Christopher F. Rose.

Outcomes of sarcopenic obesity and metabolic syndrome in liver transplant patients.

Outcomes of sarcopenic obesity and metabolic syndrome in liver transplant patients.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher Rose, Chantal Bémeur.

New insights on the impact of sex on chronic liver disease and hepatic encephalopathy.

New insights on the impact of sex on chronic liver disease and hepatic encephalopathy.

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Diabetes is associated to the development of hepatic encephalopathy in cirrhotic patients.

Diabetes is associated to the development of hepatic encephalopathy in cirrhotic patients.

Cristina R. Bosoi, Corina Cerlat, Mimosa Nguyen, Mélanie Tremblay, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Diabetes is associated to the development of hepatic encephalopathy in cirrhotic patients.

Corina Cerlat, Cristina R. Bosoi, Mimosa Nguyen, Mélanie Tremblay, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Sarcopenic obesity and metabolic syndrome: what is the impact in the context of liver transplantation?

Sarcopenic obesity and metabolic syndrome: what is the impact in the context of liver transplantation?

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

OpenAccess
An Investigation of PS‐b‐PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia

An Investigation of PS‐b‐PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia

Simon Matoori, Yinyin Bao, Aaron Schmidt, Eric J. Fischer, Rafael Ochoa-Sanchez, Mélanie Tremblay, Mariana M. Oliveira, Christopher F. Rose, Jean‐Christophe Leroux.

The attenuation of hyperammonemia by genetically engineered E. coli Nissle counters memory deficits in an experimental model of cirrhosis and hepatic encephalopathy.

The attenuation of hyperammonemia by genetically engineered E. coli Nissle counters memory deficits in an experimental model of cirrhosis and hepatic encephalopathy.

Rafael Ochoa-Sanchez, Alexis Monnet, Farzaneh Tamnanloo, Mariana M. Oliveira, Mélanie Tremblay, Mylene Perreault, Bill Querbes, Caroline Kurtz, Christopher F. Rose.

Uncovering the impact of sex-based differences in a rat model of chronic liver disease and hepatic encephalopathy.

Uncovering the impact of sex-based differences in a rat model of chronic liver disease and hepatic encephalopathy.

Mariana Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Developing a New Animal Model of Episodic Hepatic Encephalopathy.

Developing a New Animal Model of Episodic Hepatic Encephalopathy.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Obesity accelerates and exacerbates neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Obesity accelerates and exacerbates neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Alexis Monnet, Farzaneh Tamnanloo, Mariana M. Oliveira, Mylene Perreault, Bill Querbes, Caroline B. Kurtz, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Genetically Engineered E. coli Nissle attenuates hyperammonemia and improves memory in an experimental model of cirrhosis and hepatic encephalopathy.

Genetically Engineered E. coli Nissle attenuates hyperammonemia and improves memory in an experimental model of cirrhosis and hepatic encephalopathy.

Rafael Ochoa-Sanchez, Alexis Monnet, Farzaneh Tamnanloo, Mariana M. Oliveira, Mélanie Tremblay, Mylene Perreault, Bill Querbes, Caroline B. Kurtz, Christopher F. Rose.

Oral
Uncovering sex-based differences in a rat model of chronic liver disease and hepatic encephalopathy

Uncovering sex-based differences in a rat model of chronic liver disease and hepatic encephalopathy

Mariana M. Oliveira, Alexis Monnet-Aimard, Mélanie Tremblay, Christopher F. Rose.

Characterization of a novel animal model of episodic hepatic encephalopathy.

Characterization of a novel animal model of episodic hepatic encephalopathy.

Farzaneh Tamnanloo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Obesity-induced cirrhosis results in more complex and poor neurological performance related to hepatic encephalopathy in cirrhosis.

Obesity-induced cirrhosis results in more complex and poor neurological performance related to hepatic encephalopathy in cirrhosis.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Glutamine synthetase in the blood-brain barrier: role in hindering hyperammonemia-induced neurotoxicity?

Glutamine synthetase in the blood-brain barrier: role in hindering hyperammonemia-induced neurotoxicity?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Characterization of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Characterization of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Malnutrition in chronic liver disease: Implications for quality of life and hepatic encephalopathy

Malnutrition in chronic liver disease: Implications for quality of life and hepatic encephalopathy

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher Rose, Chantal Bémeur.

Sarcopenia in the context of liver transplantation: What is the prognosis?

Sarcopenia in the context of liver transplantation: What is the prognosis?

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher Rose, Chantal Bémeur.

Uncovering the protective mechanism of the BBB against ammonia neurotoxicity.

Uncovering the protective mechanism of the BBB against ammonia neurotoxicity.

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Association entre la sarcopénie et le pronostic des patients cirrhotiques dans le contexte de la transplantation hépatique.

Association entre la sarcopénie et le pronostic des patients cirrhotiques dans le contexte de la transplantation hépatique.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Évaluation d’un guide éducatif en nutrition destiné aux gens atteints de maladie hépatique chronique.

Évaluation d’un guide éducatif en nutrition destiné aux gens atteints de maladie hépatique chronique.

Manila Sophasath, Mélanie Tremblay, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Sarcopenia is associated with a worst prognosis in cirrhotic patients in the context of liver transplantation.

Sarcopenia is associated with a worst prognosis in cirrhotic patients in the context of liver transplantation.

Mimosa Nguyen, Mélanie Tremblay, An Tang, Christopher F. Rose, Chantal Bémeur.

Oral
The association between liver type fatty acid binding protein (FABP1) serum levels and clinical outcomes in patients with non-acetaminophen acute liver failure: a cohort study.

The association between liver type fatty acid binding protein (FABP1) serum levels and clinical outcomes in patients with non-acetaminophen acute liver failure: a cohort study.

Constantine Karvellas, Jaime Speiser, William M. Lee, Mélanie Tremblay, Christopher F. Rose.

The association between sarcopenia and the prognosis of cirrhotic patients in liver transplantation.

The association between sarcopenia and the prognosis of cirrhotic patients in liver transplantation.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Association entre la sarcopénie et le pronostic des patients cirrhotiques dans le contexte de la transplantation hépatique.

Association entre la sarcopénie et le pronostic des patients cirrhotiques dans le contexte de la transplantation hépatique.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Impact of gender on development of chronic liver disease and hepatic encephalopathy following bile duct ligation.

Impact of gender on development of chronic liver disease and hepatic encephalopathy following bile duct ligation.

Mariana Oliveira, Mélanie Tremblay, Christopher Rose.

Evaluate the efficiency of Rifaximin treatment in a bile-duct ligated model of cirrhosis.

Evaluate the efficiency of Rifaximin treatment in a bile-duct ligated model of cirrhosis.

Grégory Petrazzo, Mariana M. Oliveira, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Progressive resistance training prevents loss of muscle mass and strength in bile duct ligated rats.

Progressive resistance training prevents loss of muscle mass and strength in bile duct ligated rats.

Mariana M. Oliveira, Christopher F. Rose, Luise Aamann, Rafael Ochoa-Sanchez, Mariana Oliveira, Mélanie Tremblay, Chantal Bémeur, Gitte Dam, Hendrik Vilstrup, Niels Kristian Aagaard, Christopher Rose.

Nutritional status in patients with chronic liver disease: Impact on hepatic encephalopathy and health-related quality of life.

Nutritional status in patients with chronic liver disease: Impact on hepatic encephalopathy and health-related quality of life.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Alcohol accelerates hepatic encephalopathy in a rat bile duct ligation model.

Alcohol accelerates hepatic encephalopathy in a rat bile duct ligation model.

Xiaoru Chen, Mariana Oliveira, Grégory Petrazzo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher Rose.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Oral
Evaluate the efficiency of rifaximin treatment in a bile-duct ligated model of hepatic encephalopathy.

Evaluate the efficiency of rifaximin treatment in a bile-duct ligated model of hepatic encephalopathy.

Grégory Petrazzo, Mariana M. Oliveira, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Impact de l

Impact de l'état nutritionnel sur la qualité de vie et l'encéphalopathie hépatique lors de maladies chroniques du foie.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral
Glutamine synthetase in the blood-brain barrier: targeting endothelial cells for the treatment of hepatic encephalopathy?

Glutamine synthetase in the blood-brain barrier: targeting endothelial cells for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Christopher F. *Rose, Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Christopher F. *Rose, Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Christopher F. Rose.

Impact de l’exercice sur la protection du cerveau lors de maladie hépatique chronique expérimentale.

Charlène Blanchette, Luise Aamann, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Nouveau modèle d’encéphalopathie hépatique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Caractérisation de la microglie dans un modèle expérimental du syndrome de leigh version canadienne française.

Raluca Ticala, Mélanie Tremblay, Christopher F. Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: role in protecting the brain from hyperammonemia-induced neurotoxicity?

Glutamine synthetase in endothelial cells of the blood-brain barrier: role in protecting the brain from hyperammonemia-induced neurotoxicity?

Mariana Macedo de Oliveira, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study.

The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, U. S. Acute Liver Failure Study Group.

Glutamine synthetase in endothelial cells of the blood-brain barrier: role in preventing protecting the brain in hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Oral

Characterization of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Christopher F. Rose.

Oral
Hepatic encephalopathy and health-related quality of life among cirrhotic patients: Scope of nutritional status.

Hepatic encephalopathy and health-related quality of life among cirrhotic patients: Scope of nutritional status.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher Rose, Chantal Bémeur.

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher Rose.

Nouveau modèle d’encéphalopathie hépartique épisodique due à la cirrhose.

Nouveau modèle d’encéphalopathie hépartique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Impact de l’état nutritionnel sur l’encéphalopathie hépatique et la qualité de vie chez les patients atteints de maladie chronique du foie : Résultats préliminaires d’une étude prospective.

Impact de l’état nutritionnel sur l’encéphalopathie hépatique et la qualité de vie chez les patients atteints de maladie chronique du foie : Résultats préliminaires d’une étude prospective.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral
Impact de l

Impact de l'état nutritionnel sur l'encéphalopathie hépatique et la qualité de vie chez les patients atteints de maladie chronique du foie: résultats préliminaires d'une étude prospective.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher Rose, Chantal Bémeur.

Comparaison d’outils d’évaluation nutritionnelle lors de cirrhose.

Comparaison d’outils d’évaluation nutritionnelle lors de cirrhose.

Annie Lamoussenerie, Cassandra Picinbono-Larose, Mélanie Tremblay, Thierry Cresson, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

New animal model of obesity and chronic liver disease to provide insights on non-alcoholic liver disease-induced hepatic encephalopathy.

New animal model of obesity and chronic liver disease to provide insights on non-alcoholic liver disease-induced hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Marcos Ocana-Sanchez, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant?

Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant?

Christopher F. *Rose, Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis.

The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis.

Cristina R. Bosoi, Mariana M. Oliveira, Rafael Ochoa-Sanchez, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. Rose, Chantal Bémeur.

In reply: Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure.

In reply: Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure.

U. S. Acute Liver Failure Study Group, Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, U. S. Acute Liver Failure Study Group.

Brain-type Fatty Acid Binding Protein (FABP7) and Neurological Complications of Acetaminophen-induced Acute Liver Failure.

Brain-type Fatty Acid Binding Protein (FABP7) and Neurological Complications of Acetaminophen-induced Acute Liver Failure.

Constantine Jason Karvellas, Jaime Lynn Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose.

Elevated Liver Fatty Acid Binding Protein (FABP1) Serum Levels Improve Prognostic Discrimination of King’s College Criteria and the ALSFG Index in Acetaminophen-induced Acute Liver Failure: A Nested Case Control Study.

Elevated Liver Fatty Acid Binding Protein (FABP1) Serum Levels Improve Prognostic Discrimination of King’s College Criteria and the ALSFG Index in Acetaminophen-induced Acute Liver Failure: A Nested Case Control Study.

Constantine Jason Karvellas, Jaime Lynn Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose.

Oral
Oral Ornithine Phenylacetate Attenuates Muscle Mass Loss and Prevents Hepatic Encephalopathy in BDL Rats.

Oral Ornithine Phenylacetate Attenuates Muscle Mass Loss and Prevents Hepatic Encephalopathy in BDL Rats.

Marc-André Clément, Cristina R. Bosoi, Mariana Oliveira, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. Rose.

Impact of nutritional status on hepatic encephalopathy and quality of life in patients with chronic liver disease: preliminary results of a prospective study.

Impact of nutritional status on hepatic encephalopathy and quality of life in patients with chronic liver disease: preliminary results of a prospective study.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Demers, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral
Effects of anaerobic exercise in muscle mass optimization in bile duct ligated rats.

Effects of anaerobic exercise in muscle mass optimization in bile duct ligated rats.

Mariana Oliveira, Christopher Rose, Luise Aamann, Rafael Ochoa-Sanchez, Mariana M. Oliveira, Mélanie Tremblay, Chantal Bémeur, Gitte Dam, Hendrik Vilstrup, Niels Kristian Aagaard, Christopher F. Rose.

Oral
Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant ?

Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant ?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Nutritional status assessment in patients with chronic liver disease: a pilot study.

Nutritional status assessment in patients with chronic liver disease: a pilot study.

Annie Lamoussenerie, Cassandra Picinbono-Larose, Mélanie Tremblay, Catherine Demers, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Development of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Development of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Marcos Ocana-Sanchez, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Oral

Liver type fatty acid binding protein (FABP1) levels improve performance of prognostic models in acetaminophen induced acute liver failure.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Elaine M. Leslie, Christopher F. Rose.

Oral

Nouveau modèle d’encéphalopathie hépatique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Brain-FABP serum levels and clinical outcomes in acetaminophen-induced acute liver failure.

Constantine Karvellas, Jaime Speiser, Mélanie Tremblay, William Lee, Christopher Rose.

Oral
Elevated Liver Fatty Acid Binding protein serum levels improve prognostic discrimination of King’s College Criteria and the ALFSG index in acetaminophen-induced acute liver failure: a case control study.

Elevated Liver Fatty Acid Binding protein serum levels improve prognostic discrimination of King’s College Criteria and the ALFSG index in acetaminophen-induced acute liver failure: a case control study.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Elaine M. Leslie, Christopher F. Rose.

The association between Brain Fatty Acid Binding protein serum levels with survival and intracranial hypertension in acetaminophen-induced acute liver failure patients: a case control study.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Gurnit Kaur, Elaine M. Leslie, Christopher Rose, US Acute Liver Failure Study Group.

Évaluation de l

Évaluation de l'état nutritionnel lors de cirrhose.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Developing a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Developing a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Mariana Oliveira, Cristina Bosoi, Marc-André Clément, Christopher F. Rose.

The role of the blood-brain barrier in ammonia homeostasis: targeting endothelial cells for the treatment of hepatic encephalopathy.

The role of the blood-brain barrier in ammonia homeostasis: targeting endothelial cells for the treatment of hepatic encephalopathy.

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Evaluation of nutritional status in patients with chronic liver disease: a pilot study.

Evaluation of nutritional status in patients with chronic liver disease: a pilot study.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Oral
Beneficial effects of ornithine phenylacetate to attenuate muscle mass loss and to prevent hepatic encephalopathy in experimental cirrhosis.

Beneficial effects of ornithine phenylacetate to attenuate muscle mass loss and to prevent hepatic encephalopathy in experimental cirrhosis.

Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. *Rose.

Évaluation de l

Évaluation de l'état nutritionnel lors de cirrhose.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Oral
Ornithine phenylacetate attenuates loss of muscle mass and improves hepatic encephalopathy in bile-duct ligated rats.

Ornithine phenylacetate attenuates loss of muscle mass and improves hepatic encephalopathy in bile-duct ligated rats.

Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabrie Ten Have, Nicholaas Deutz, Christopher F. Rose.

Oral
Minimal hepatic encephalopathy renders the brain susceptible to hypotension-induced neuronal cell loss in BDL rats.

Minimal hepatic encephalopathy renders the brain susceptible to hypotension-induced neuronal cell loss in BDL rats.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

Leucine et exercices : bénéfique lors d'encéphalopathie expérimentale.

Corine Fontaine, Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral

Neuroinflammation et activation microgliale chez des rats cirrhotiques soumis à une hypotension.

Maxime Hovington, Marc-André Clément, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Liposome-supported peritoneal dialysis for the treatment of hepatic encephalopathy.

Liposome-supported peritoneal dialysis for the treatment of hepatic encephalopathy.

Valentina Agostoni, Soo Hyeon Lee, Vincent Forster, Meriam Kabbaj, Cristina Bosoi, Mélanie Tremblay, Matthias Zadory, Christopher F. Rose, Jean-Christophe Leroux.

Oral
Minimal hepatic encephalopathy leads to hypotension-induced neuronal cell loss in BDL rats.

Minimal hepatic encephalopathy leads to hypotension-induced neuronal cell loss in BDL rats.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Long term oral treatment of ornithine phenylacetate increases lean mass and attenuates brain edema in bile-duct ligated rats.

Long term oral treatment of ornithine phenylacetate increases lean mass and attenuates brain edema in bile-duct ligated rats.

Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabrie Ten Have, Nicolaas E. P. Deutz, Christopher F. Rose.

Liposome-Supported Peritoneal Dialysis in the Treatment of Severe Hyperammonemia.

Valentina Agostoni, Vincent Forster, Cristina Bosoi, Mélanie Tremblay, Christopher Rose, Jean-Christophe Leroux.

Impact d

Impact d'un stress inflammatoire et nutritionnel dans un modèle cellulaire d'acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Impact d’un stress de type inflammatoire et nutritionnel dans un modèle cellulaire d’acidose lactique.

Impact d’un stress de type inflammatoire et nutritionnel dans un modèle cellulaire d’acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral
Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral
Impact d

Impact d'un stress inflammatoire et nutritionnel dans un modèle cellulaire d'acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Muscle mass optimization prevents experimental hepatic encephalopathy.

Muscle mass optimization prevents experimental hepatic encephalopathy.

Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Bile-ligated rats are susceptible to hypotension-induced neuronal cell loss: implications for persisting neurological complications following liver transplantation.

Bile-ligated rats are susceptible to hypotension-induced neuronal cell loss: implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Effet du stress oxydatif et de l'ammoniaque sur la perméabilité de la barrière hémato-encéphalique dans la maladie de foie chronique.

Valérie Boucher, Mélanie Tremblay, Christopher F. Rose.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Caractérisation d

Caractérisation d'un modèle cellulaire de stress de type inflammatoire et nutritionnel lors du syndrome de leigh version canadienne française.

Rafaela Almeida, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur, Consortium de l'acidose lactique.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased BBB permeability via NKCC1.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased BBB permeability via NKCC1.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral
Optimizing muscle mass: therapeutic target to prevent experimental hepatic encephalopathy.

Optimizing muscle mass: therapeutic target to prevent experimental hepatic encephalopathy.

Chantal *Bémeur, Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased bbb permeability via NKCC1.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased bbb permeability via NKCC1.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Beneficial effects of muscle mass optimization using leucine supplementation and exercise training in the prevention of hepatic encephalopathy in experimental cirrhosis.

Beneficial effects of muscle mass optimization using leucine supplementation and exercise training in the prevention of hepatic encephalopathy in experimental cirrhosis.

Chantal *Bémeur, Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral
Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral
The novel glutaminase inhibitor CB-839 prevents oral glutamine-induced hyperammonemia in portacaval shunted rats.

The novel glutaminase inhibitor CB-839 prevents oral glutamine-induced hyperammonemia in portacaval shunted rats.

Cristina R. Bosoi, Marc-André Clément, Mélanie Tremblay, Christopher F. Rose.

Systemic oxidative stress induction leads to brain edema in hyperammonemic portacaval-shunted rats.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Implication de l

Implication de l'hypotension dans la pathogenèse de l'encéphalopathie hépatique.

Marc-André Clément, Mélanie Tremblay, Christopher F. Rose.

Glutathione depletion leads to brain edema in portacaval-shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Beneficial effects of muscle mass optimization using leucine supplementation and exercise training in the prevention of hepatic encephalopathy in experimental cirrhosis.

Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Inhibiting lactate synthesis: a new therapeutic target for the treatment of hepatic encephalopathy.

Inhibiting lactate synthesis: a new therapeutic target for the treatment of hepatic encephalopathy.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Impact of muscle mass optimization in the prevention of hepatic encephalopathy in experimental cirrhosis.

Impact of muscle mass optimization in the prevention of hepatic encephalopathy in experimental cirrhosis.

Chantal Bémeur, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.

Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.

Cristina R. Bosoi, Claudia Zwingmann, Helen Marin, Christian Parent-Robitaille, Jimmy Huynh, Mélanie Tremblay, Christopher F. Rose.

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats.

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
L

L'impact de l’isoleucine et de l’exercice physique sur l’état métabolique, la masse musculaire et l’encéphalopathie hépatique chez des rats cirrhotiques.

Cristina R. *Bosoi, Chantal Bémeur, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Impact of isoleucine and exercise on metabolic state, muscle mass and hepatic encephalopathy in cirrhotic rats.

Impact of isoleucine and exercise on metabolic state, muscle mass and hepatic encephalopathy in cirrhotic rats.

Chantal Bémeur, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
Systemic oxidative stress induction aggravates hepatic encephalopathy in hyperammonemic portacaval-shunted rats.

Systemic oxidative stress induction aggravates hepatic encephalopathy in hyperammonemic portacaval-shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Oral
Chronic hyperammonemia “priming” alleviates the induction of oxidative stress and development of brain edema following an acute liver insult.

Chronic hyperammonemia “priming” alleviates the induction of oxidative stress and development of brain edema following an acute liver insult.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Oral

Le méthylglyoxal et l'encéphalopathie hépatique.

Vi T. Tran, Laurent Bilodeau, Cristina R. Bosoi, Mélanie Tremblay, Mireille Bélanger, Christopher F. Rose.

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L'encéphalopathie hépatique sévère est retardée chez des rats souffrant d’une décompensation hépatique aigue durant une hyperammoniémie chronique.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Le méthylglyoxal et l

Le méthylglyoxal et l'encéphalopathie hépatique.

Vi T. Tran, Laurent Bilodeau, Cristina R. Bosoi, Mélanie Tremblay, Mireille Bélanger, Christopher F. Rose.

Onset of severe hepatic encephalopathy is delayed in rats with acute liver insult superimposed on chronic hyperammonemia compared to rats with acute liver failure: a look at underlying mechanisms.

Onset of severe hepatic encephalopathy is delayed in rats with acute liver insult superimposed on chronic hyperammonemia compared to rats with acute liver failure: a look at underlying mechanisms.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Role of cerebral lactate in the pathogenesis of brain edema in cirrhotic rats.

Role of cerebral lactate in the pathogenesis of brain edema in cirrhotic rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Implication de la glutaminase dans l

Implication de la glutaminase dans l'insuffisance hépatique chronique.

Ada Rivera, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

L

L'inhibition de la xanthine oxydase atténue l'oedème cérébral chez des rats avec insuffisance hépatique chronique.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Le rôle de l

Le rôle de l'encéphalopathie hépatique dans la susceptibilité accrue à l’insulte neuronale induite par hypotension/ hypoxie cérébrale.

Christian Parent-Robitaille, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
Increased cerebral lactate contributes to brain edema in cirrhotic rats.

Increased cerebral lactate contributes to brain edema in cirrhotic rats.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
Systemic oxidative stress induction leads to brain edema in hyperammonemic portacaval-shunted rats.

Systemic oxidative stress induction leads to brain edema in hyperammonemic portacaval-shunted rats.

Cristina Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral
Role of oxidative stress in prevention of brain edema during an acute deterioration of chronic liver failure.

Role of oxidative stress in prevention of brain edema during an acute deterioration of chronic liver failure.

Cristina R. *Bosoi, Chantal Bémeur, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
Le rôle du stress oxydatif dans la pathogenèse de l’œdème cérébral dans l’encéphalopathie hépatique.

Le rôle du stress oxydatif dans la pathogenèse de l’œdème cérébral dans l’encéphalopathie hépatique.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral
Xanthine oxidase inhibition attenuates brain edema in in rats with liver failure.

Xanthine oxidase inhibition attenuates brain edema in in rats with liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral
Glutathione depletion leads to brain edema in portacaval-shunted rats.

Glutathione depletion leads to brain edema in portacaval-shunted rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure.

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure.

Cristina R. Bosoi, Xiaoling Yang, Jimmy Huynh, Christian Parent-Robitaille, Wenlei Jiang, Mélanie Tremblay, Christopher F. Rose.

Evidence systemic oxidative stress represents a “first hit” in the multifactorial pathogenesis of brain edema in chronic liver failure.

Evidence systemic oxidative stress represents a “first hit” in the multifactorial pathogenesis of brain edema in chronic liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Allopurinol attenuates systemic oxidative stress and hyperammonemia in bile-duct ligated rats.

Allopurinol attenuates systemic oxidative stress and hyperammonemia in bile-duct ligated rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Systemic oxidative stress followed by increases in ammonia and lactate is involved in the pathogenesis of brain edema in chronic liver failure.

Systemic oxidative stress followed by increases in ammonia and lactate is involved in the pathogenesis of brain edema in chronic liver failure.

Claudia Zwingmann, Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Oral
Impaired lactate metabolism, not brain ammonia and glutamine, contributes to the pathogenesis of brain edema in minimal hepatic encephalopathy.

Impaired lactate metabolism, not brain ammonia and glutamine, contributes to the pathogenesis of brain edema in minimal hepatic encephalopathy.

Christian Parent-Robitaille, Cristina R. Bosoi, Claudia Zwingmann, Jimmy Huynh, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Oral
Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.