Hepato-neuro lab

Mélanie Tremblay, M.Sc.

 

Related Publications

The association between sarcopenia and the prognosis of cirrhotic patients in liver transplantation.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Association entre la sarcopénie et le pronostic des patients cirrhotiques dans le contexte de la transplantation hépatique.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Impact of gender on development of chronic liver disease and hepatic encephalopathy following bile duct ligation.

Mariana Oliveira, Mélanie Tremblay, Christopher Rose.

Progressive resistance training prevents loss of muscle mass and strength in bile duct ligated rats.

Luise Aamann, Rafael Ochoa-Sanchez, Mariana Oliveira, Mélanie Tremblay, Chantal Bémeur, Gitte Dam, Hendrik Vilstrup, Niels Kristian Aagaard, Christopher Rose.

Nutritional status in patients with chronic liver disease: Impact on hepatic encephalopathy and health-related quality of life.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Alcohol accelerates hepatic encephalopathy in a rat bile duct ligation model.

Xiaoru Chen, Mariana Oliveira, Grégory Petrazzo, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher Rose.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Oral

Evaluate the efficiency of rifaximin treatment in a bile-duct ligated model of hepatic encephalopathy.

Grégory Petrazzo, Mariana M. Oliveira, Rafael Ochoa-Sanchez, Mélanie Tremblay, F. Rose Christopher.

Impact de la sarcopénie lors de la transplantation hépatique : une étude rétrospective en cours.

Mimosa Nguyen, Mélanie Tremblay, Geneviève Huard, An Tang, Christopher F. Rose, Chantal Bémeur.

Impact de l'état nutritionnel sur la qualité de vie et l'encéphalopathie hépatique lors de maladies chroniques du foie.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Christopher F. *Rose, Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Christopher F. Rose.

Oral

Glutamine synthetase in the blood-brain barrier: targeting endothelial cells for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Christopher F. *Rose, Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Impact de l’exercice sur la protection du cerveau lors de maladie hépatique chronique expérimentale.

Charlène Blanchette, Luise Aamann, Mélanie Tremblay, Christopher Rose F., Chantal Bémeur.

Nouveau modèle d’encéphalopathie hépatique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Caractérisation de la microglie dans un modèle expérimental du syndrome de leigh version canadienne française.

Raluca Ticala, Mélanie Tremblay, Christopher F. Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Nutritional status, hepatic encephalopathy and health-related quality of life in patients with chronic liver disease.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Glutamine synthetase in endothelial cells of the blood-brain barrier: role in protecting the brain from hyperammonemia-induced neurotoxicity?

Mariana Macedo de Oliveira, Mélanie Tremblay, Christopher F. Rose.

Obesity exacerbates the neurological impairments associated to hepatic encephalopathy in chronic liver disease.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study.

The association between FABP7 serum levels with survival and neurological complications in acetaminophen-induced acute liver failure: a nested case-control study.

U. S. Acute Liver Failure Study Group, Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, U. S. Acute Liver Failure Study Group.

Oral

Characterization of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: role in preventing protecting the brain in hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Oral

Hepatic encephalopathy and health-related quality of life among cirrhotic patients: Scope of nutritional status.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher Rose, Chantal Bémeur.

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher Rose.

Nouveau modèle d’encéphalopathie hépartique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Impact de l’état nutritionnel sur l’encéphalopathie hépatique et la qualité de vie chez les patients atteints de maladie chronique du foie : Résultats préliminaires d’une étude prospective.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Comparaison d’outils d’évaluation nutritionnelle lors de cirrhose.

Annie Lamoussenerie, Cassandra Picinbono-Larose, Mélanie Tremblay, Thierry Cresson, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral

Impact de l'état nutritionnel sur l'encéphalopathie hépatique et la qualité de vie chez les patients atteints de maladie chronique du foie: résultats préliminaires d'une étude prospective.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Vincent, Geneviève Huard, Christopher Rose, Chantal Bémeur.

The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis.

The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis.

Cristina R. Bosoi, Mariana M. Oliveira, Rafael Ochoa-Sanchez, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. Rose, Chantal Bémeur.

In reply: Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure.

U. S. Acute Liver Failure Study Group, Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, U. S. Acute Liver Failure Study Group.

New animal model of obesity and chronic liver disease to provide insights on non-alcoholic liver disease-induced hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Marcos Ocana-Sanchez, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant?

Christopher F. *Rose, Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Oral

Oral Ornithine Phenylacetate Attenuates Muscle Mass Loss and Prevents Hepatic Encephalopathy in BDL Rats.

Marc-André *Clément, Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. Rose.

Elevated Liver Fatty Acid Binding Protein (FABP1) Serum Levels Improve Prognostic Discrimination of King’s College Criteria and the ALSFG Index in Acetaminophen-induced Acute Liver Failure: A Nested Case Control Study.

Constantine Jason Karvellas, Jaime Lynn Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose.

Brain-type Fatty Acid Binding Protein (FABP7) and Neurological Complications of Acetaminophen-induced Acute Liver Failure.

Constantine Jason Karvellas, Jaime Lynn Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose.

Nutritional status assessment in patients with chronic liver disease: a pilot study.

Annie Lamoussenerie, Cassandra Picinbono-Larose, Mélanie Tremblay, Catherine Demers, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Development of a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Marc-André Clément, Marcos Ocana-Sanchez, Christopher F. Rose.

Oral

Glutamine synthetase in endothelial cells of the blood-brain barrier: less but not insignificant ?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Impact of nutritional status on hepatic encephalopathy and quality of life in patients with chronic liver disease: preliminary results of a prospective study.

Cassandra Picinbono-Larose, Annie Lamoussenerie, Mélanie Tremblay, Catherine Demers, Catherine Vincent, Geneviève Huard, Christopher F. Rose, Chantal Bémeur.

Oral

Effects of anaerobic exercise in muscle mass optimization in bile duct ligated rats.

Luise Aamann, Rafael Ochoa-Sanchez, Mariana M. Oliveira, Mélanie Tremblay, Chantal Bémeur, Gitte Dam, Hendrik Vilstrup, Niels Kristian Aagaard, Christopher F. Rose.

Glutamine synthetase in endothelial cells of the blood-brain barrier: new target for the treatment of hepatic encephalopathy?

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Oral

Liver type fatty acid binding protein (FABP1) levels improve performance of prognostic models in acetaminophen induced acute liver failure.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Elaine M. Leslie, Christopher F. Rose.

Oral

Nouveau modèle d’encéphalopathie hépatique épisodique due à la cirrhose.

Kim Phat Pham, Rafael Ochoa-Sanchez, Mélanie Tremblay, Christopher F. Rose.

Brain-FABP serum levels and clinical outcomes in acetaminophen-induced acute liver failure.

Constantine Karvellas, Jaime Speiser, Mélanie Tremblay, William Lee, Christopher Rose.

Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure.

Elevated FABP1 serum levels are associated with poorer survival in acetaminophen-induced acute liver failure.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Christopher F. Rose, for US Acute Liver Failure Study Group.

Oral

Elevated Liver Fatty Acid Binding protein serum levels improve prognostic discrimination of King’s College Criteria and the ALFSG index in acetaminophen-induced acute liver failure: a case control study.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Elaine M. Leslie, Christopher F. Rose.

The association between Brain Fatty Acid Binding protein serum levels with survival and intracranial hypertension in acetaminophen-induced acute liver failure patients: a case control study.

Constantine J. Karvellas, Jaime L. Speiser, Mélanie Tremblay, William M. Lee, Gurnit Kaur, Elaine M. Leslie, Christopher Rose, US Acute Liver Failure Study Group.

Evaluation of nutritional status in patients with chronic liver disease: a pilot study.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Évaluation de l'état nutritionnel lors de cirrhose.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Developing a new animal model of obesity and chronic liver disease for the study of hepatic encephalopathy.

Rafael Ochoa-Sanchez, Mélanie Tremblay, Mariana Oliveira, Cristina Bosoi, Marc-André Clément, Christopher F. Rose.

The role of the blood-brain barrier in ammonia homeostasis: targeting endothelial cells for the treatment of hepatic encephalopathy.

Mariana Oliveira, Mélanie Tremblay, Christopher F. Rose.

Évaluation de l'état nutritionnel lors de cirrhose.

Annie Lamoussenerie, Mélanie Tremblay, Thierry Cresson, An Tang, Catherine Vincent, Christopher F. Rose, Chantal Bémeur.

Oral

Beneficial effects of ornithine phenylacetate to attenuate muscle mass loss and to prevent hepatic encephalopathy in experimental cirrhosis.

Christopher F. *Rose, Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabriella A. Ten Have, Nicolaas E. Deutz, Christopher F. Rose.

Oral

Ornithine phenylacetate attenuates loss of muscle mass and improves hepatic encephalopathy in bile-duct ligated rats.

Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabrie Ten Have, Nicholaas Deutz, Christopher F. Rose.

Oral

Minimal hepatic encephalopathy renders the brain susceptible to hypotension-induced neuronal cell loss in BDL rats.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

Leucine et exercices : bénéfique lors d'encéphalopathie expérimentale.

Corine Fontaine, Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Oral

Neuroinflammation et activation microgliale chez des rats cirrhotiques soumis à une hypotension.

Maxime Hovington, Marc-André Clément, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Liposome-supported peritoneal dialysis for the treatment of hepatic encephalopathy.

Liposome-supported peritoneal dialysis for the treatment of hepatic encephalopathy.

Valentina Agostoni, Soo Hyeon Lee, Vincent Forster, Meriam Kabbaj, Cristina Bosoi, Mélanie Tremblay, Matthias Zadory, Christopher F. Rose, Jean-Christophe Leroux.

Long term oral treatment of ornithine phenylacetate increases lean mass and attenuates brain edema in bile-duct ligated rats.

Cristina R. Bosoi, Mariana Oliveira, Marc-André Clément, Mélanie Tremblay, Gabrie Ten Have, Nicolaas E. P. Deutz, Christopher F. Rose.

Oral

Minimal hepatic encephalopathy leads to hypotension-induced neuronal cell loss in BDL rats.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Impact d'un stress inflammatoire et nutritionnel dans un modèle cellulaire d'acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Liposome-Supported Peritoneal Dialysis in the Treatment of Severe Hyperammonemia.

Valentina Agostoni, Vincent Forster, Cristina Bosoi, Mélanie Tremblay, Christopher Rose, Jean-Christophe Leroux.

Impact d’un stress de type inflammatoire et nutritionnel dans un modèle cellulaire d’acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

Impact d'un stress inflammatoire et nutritionnel dans un modèle cellulaire d'acidose lactique.

Rafaela Almeida, Mélanie Tremblay, Christopher Rose, Consortium de l'acidose lactique, Chantal Bémeur.

Oral

Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Bile-ligated rats are susceptible to hypotension-induced neuronal cell loss: implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Muscle mass optimization prevents experimental hepatic encephalopathy.

Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Effet du stress oxydatif et de l'ammoniaque sur la perméabilité de la barrière hémato-encéphalique dans la maladie de foie chronique.

Valérie Boucher, Mélanie Tremblay, Christopher F. Rose.

Caractérisation d'un modèle cellulaire de stress de type inflammatoire et nutritionnel lors du syndrome de leigh version canadienne française.

Rafaela Almeida, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur, Consortium de l'acidose lactique.

Diminution du compte neuronal par une insulte hypotensive chez le rat avec ligation de la voie biliaire: implications pour la persistance des complications neurologiques après transplantation hépatique.

Marc-André Clément, Cristina R. Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Oral

Optimizing muscle mass: therapeutic target to prevent experimental hepatic encephalopathy.

Chantal *Bémeur, Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased BBB permeability via NKCC1.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

The novel glutaminase inhibitor CB-839 prevents oral glutamine-induced hyperammonemia in portacaval shunted rats.

Cristina R. Bosoi, Marc-André Clément, Mélanie Tremblay, Christopher F. Rose.

Oral

Bile-duct ligated rats are susceptible to hypotension-induced neuronal cell loss: Implications for persisting neurological complications following liver transplantation.

Marc-André Clément, Cristina Bosoi, Mélanie Tremblay, Chantal Bémeur, Christopher F. Rose.

Beneficial effects of muscle mass optimization using leucine supplementation and exercise training in the prevention of hepatic encephalopathy in experimental cirrhosis.

Chantal *Bémeur, Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Bumetanide normalizes brain edema in rats with bile duct ligation: evidence for increased bbb permeability via NKCC1.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Systemic oxidative stress induction leads to brain edema in hyperammonemic portacaval-shunted rats.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Glutathione depletion leads to brain edema in portacaval-shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Beneficial effects of muscle mass optimization using leucine supplementation and exercise training in the prevention of hepatic encephalopathy in experimental cirrhosis.

Sara Ghezzal, Marc-André Clément, Cristina R. Bosoi, Roxanne Beauchamp, Mélanie Tremblay, Christopher F. Rose, Chantal Bémeur.

Implication de l'hypotension dans la pathogenèse de l'encéphalopathie hépatique.

Marc-André Clément, Mélanie Tremblay, Christopher F. Rose.

Impact of muscle mass optimization in the prevention of hepatic encephalopathy in experimental cirrhosis.

Chantal Bémeur, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Inhibiting lactate synthesis: a new therapeutic target for the treatment of hepatic encephalopathy.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.

Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.

Cristina R. Bosoi, Claudia Zwingmann, Helen Marin, Christian Parent-Robitaille, Jimmy Huynh, Mélanie Tremblay, Christopher F. Rose.

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats.

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

L'impact de l’isoleucine et de l’exercice physique sur l’état métabolique, la masse musculaire et l’encéphalopathie hépatique chez des rats cirrhotiques.

Cristina R. *Bosoi, Chantal Bémeur, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Impact of isoleucine and exercise on metabolic state, muscle mass and hepatic encephalopathy in cirrhotic rats.

Chantal Bémeur, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Attenuation of oxidative stress protects the brain in rats with “acute-on-chronic” liver failure.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Systemic oxidative stress induction aggravates hepatic encephalopathy in hyperammonemic portacaval-shunted rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

Chronic hyperammonemia “priming” alleviates the induction of oxidative stress and development of brain edema following an acute liver insult.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Oral

Le méthylglyoxal et l'encéphalopathie hépatique.

Vi T. Tran, Laurent Bilodeau, Cristina R. Bosoi, Mélanie Tremblay, Mireille Bélanger, Christopher F. Rose.

L'encéphalopathie hépatique sévère est retardée chez des rats souffrant d’une décompensation hépatique aigue durant une hyperammoniémie chronique.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Le méthylglyoxal et l'encéphalopathie hépatique.

Vi T. Tran, Laurent Bilodeau, Cristina R. Bosoi, Mélanie Tremblay, Mireille Bélanger, Christopher F. Rose.

Onset of severe hepatic encephalopathy is delayed in rats with acute liver insult superimposed on chronic hyperammonemia compared to rats with acute liver failure: a look at underlying mechanisms.

Cristina R. Bosoi, Chantal Bémeur, Bich Nguyen, Mélanie Tremblay, Christopher F. Rose.

Role of cerebral lactate in the pathogenesis of brain edema in cirrhotic rats.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

Role of oxidative stress in prevention of brain edema during an acute deterioration of chronic liver failure.

Cristina R. *Bosoi, Chantal Bémeur, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

Le rôle du stress oxydatif dans la pathogenèse de l’œdème cérébral dans l’encéphalopathie hépatique.

Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

Systemic oxidative stress induction leads to brain edema in hyperammonemic portacaval-shunted rats.

Cristina Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

Increased cerebral lactate contributes to brain edema in cirrhotic rats.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

L'inhibition de la xanthine oxydase atténue l'oedème cérébral chez des rats avec insuffisance hépatique chronique.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Le rôle de l'encéphalopathie hépatique dans la susceptibilité accrue à l’insulte neuronale induite par hypotension/ hypoxie cérébrale.

Christian Parent-Robitaille, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Implication de la glutaminase dans l'insuffisance hépatique chronique.

Ada Rivera, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

Glutathione depletion leads to brain edema in portacaval-shunted rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

Xanthine oxidase inhibition attenuates brain edema in in rats with liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure.

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure.

Cristina R. Bosoi, Xiaoling Yang, Jimmy Huynh, Christian Parent-Robitaille, Wenlei Jiang, Mélanie Tremblay, Christopher F. Rose.

Allopurinol attenuates systemic oxidative stress and hyperammonemia in bile-duct ligated rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Evidence systemic oxidative stress represents a “first hit” in the multifactorial pathogenesis of brain edema in chronic liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Systemic oxidative stress followed by increases in ammonia and lactate is involved in the pathogenesis of brain edema in chronic liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Oral

Na-K-Cl cotransporter is implicated in the pathogenesis of brain edema in rats with bile duct ligation.

Jimmy Huynh, Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

Impaired lactate metabolism, not brain ammonia and glutamine, contributes to the pathogenesis of brain edema in minimal hepatic encephalopathy.

Cristina R. Bosoi, Claudia Zwingmann, Jimmy Huynh, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats.

AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Keith Anderson, Mélanie Tremblay, Christopher F. Rose.

Le cotransporteur Na-K-Cl est impliqué dans la pathogénèse de l’œdème cérébral chez les rats avec une ligature de la voie biliaire.

Jimmy Huynh, Cristina Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

L'augmentation de novo du lactate cérébral, indépendamment des niveaux d’ammoniaque et glutamine, est impliquée dans la pathogénèse de l’œdème cérébral dans l’insuffisance hépatique chronique.

Cristina R. Bosoi, Claudia Zwingmann, Jimmy Huynh, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Increased de novo synthesis of brain lactate, independent of brain ammonia and glutamine, is implicated in the pathogenesis of brain edema in chronic liver failure.

Cristina R. Bosoi, Claudia Zwingmann, Jimmy Huynh, Helen Marin, Mélanie Tremblay, Christopher F. Rose.

Dose dependent effects of AST-120 (spherical carbon adsorbent) on arterial ammonia, brain edema, and systemic inflammatory marker (TNF-a) in bile duct ligated rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

AST-120 (spherical carbon adsorbent) treatment prevents hyperammonemia and brain edema in cirrhotic rats.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

OpenAccess
Portacaval anastomosis-induced hyperammonemia does not lead to oxidative stress.

Portacaval anastomosis-induced hyperammonemia does not lead to oxidative stress.

Xiaoling Yang, Cristina R. Bosoi, Wenlei Jiang, Mélanie Tremblay, Christopher F. Rose.

Oral

AST-120 (adsorbant sphérique de charbon) atténue l'œdème cérébral et diminue le niveau artériel d'ammoniaque chez les rats avec ligature de voie biliaire.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

L'œdème cérébral est associé avec le stress oxydatif systémique et non central dans les rats avec ligature de la voie biliaire.

Xiaoling Yang, Cristina R. Bosoi, Mélanie Tremblay, Christopher F. Rose.

Oral

AST-120 (spherical carbon adsorbent) attenuates brain edema and lowers arterial ammonia in bile duct ligated rats.

Christopher F. *Rose, Cristina Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Brain edema is associated with systemic and not central oxidative stress in rats with bile-duct ligation.

Xiaoling Yang, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

AST-120 (spherical carbon adsorbent) lowers arterial ammonia and attenuates brain edema in bile-duct ligated rats.

Christopher F. *Rose, Cristina Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Brain edema is associated with systemic and not central oxidative stress in rats with bile-duct ligation.

Xiaoling Yang, Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.

Synergistic effect of systemic oxidative stress and hyperammonemia leads to brain edema in rats with chronic liver failure.

Cristina R. Bosoi, Xiaoling Yang, Wenlei Jiang, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

L'effet synergique du stress oxydatif et l'hyperammonémie mène à l'œdème cérébral chez des rats avec une insuffisance hépatique chronique.

Cristina R. Bosoi, Wenlei Jiang, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Oral

Synergistic effect of systemic oxidative stress and hyperammonemia leads to brain edema in rats with chronic liver failure.

Cristina R. Bosoi, Xiaoling Yang, Wenlei Jiang, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Synergistic effect of systemic oxidative stress and hyperammonemia leads to brain edema in rats with chronic liver failure.

Cristina R. Bosoi, Christian Parent-Robitaille, Mélanie Tremblay, Christopher F. Rose.

Hyperammonemia does not induce oxidative/nitrosative stress in rats with portacaval anastomosis.

Cristina Bosoi, Mélanie Tremblay, Christopher F. Rose.