Hepato-neuro lab

Article in Hepatology-Ytrebo-2009

Accepted article

 2009-02-19
 Publication

A paper was accepted for publication in Hepatology.

The results of a Dr. Rose's project in Norway with Dr. Ytrebo has been published. He studied acute hepatic failure in pigs. Ornithine-phenylacetate, a strategy to decrease ammonia, has been shown to be effective in 1) decreasing ammonia (seric and cerebral) and 2) preventing increased intracranial pressure.

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Related Publication

OpenAccess
L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure.

L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure.

Lars Marius Ytrebø, Rune Gangsøy Kristiansen, Hanne Maehre, Ole Martin Fuskevåg, Trine Kalstad, Arthur Revhaug, María Jover Cobos, Rajiv Jalan, Christopher F. Rose.