Increased de novo synthesis of brain lactate, independent of brain ammonia and glutamine, is implicated in the pathogenesis of brain edema in chronic liver failure.
Cristina R. Bosoi, Claudia Zwingmann, Jimmy Huynh, Helen Marin, Mélanie Tremblay, Christopher F. Rose.
14th International Society for Hepatic Encephalopathy and Nitrogen Metabolism
September 14th-18th 2010
Val-David, Canada