Hepato-neuro lab


EncephalApp stroop is a mobile application (iOS/Android) is a test for mental speed and flexibility. It was shown to predict minimal hepatic encephalopathy (MHE).

We coordinated a multi-centric study around Canada to establish norms with healthy participants. An equation using age, gender and level of education was derived. You can input here results of a cirrhotic patient to predict if has MHE or not.


  1. Jasmohan S. Bajaj, Leroy R. Thacker, Douglas M. Heuman, Michael Fuchs, Richard K. Sterling, Arun J. Sanyal, Puneet Puri, Mohammad S. Siddiqui, Richard T. Stravitz, Iliana Bouneva, Velimir Luketic, Nicole Noble, Melanie B. White, Pamela Monteith, Ariel Unser, James B. Wade (2013) The Stroop smartphone application is a short and valid method to screen for minimal hepatic encephalopathy. Hepatology, 58: 1122-1132. doi: 10.1002/hep.26309
  2. Jasmohan S. Bajaj, Douglas M. Heuman, Richard K. Sterling, Arun J. Sanyal, Muhammad Siddiqui, Scott Matherly, Velimir Luketic, R. Todd Stravitz, Michael Fuchs, Leroy R. Thacker, HoChong Gilles, Melanie B. White, Ariel Unser, James Hovermale, Edith Gavis, Nicole A. Noble, James B. Wade (2015) Validation of EncephalApp, Smartphone-Based Stroop Test, for the Diagnosis of Covert Hepatic Encephalopathy. Clin Gastroenterol Hepatol, 13: 1828-1835.e1. doi: 10.1016/j.cgh.2014.05.011
  3. Sanath Allampati, Andres Duarte-Rojo, Leroy R. Thacker, Kavish R. Patidar, Melanie B. White, Jagpal S. Klair, Binu John, Douglas M. Heuman, James B. Wade, Christopher Flud, Robert O'Shea, Edith A. Gavis, Ariel B. Unser, Jasmohan S. Bajaj (2016) Diagnosis of Minimal Hepatic Encephalopathy Using Stroop EncephalApp: A Multicenter US-Based, Norm-Based Study. Am J Gastroenterol, 111: 78-86. doi: 10.1038/ajg.2015.377